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Neuropilin 1 Antibody

48067

Neuropilin 1 Antibody

Neuropilin 1 Antibody (catalogue number 48067) is a mouse-derived primary antibody validated for Western blot, Immunocytochemistry, Immunohistochemistry, reactive with Human, Mouse samples. It targets Neuropilin-1 (NRP1): Cell-surface receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. Supplied in 2 pack sizes, from 50ul at ₪1,219.60 to 100ul at ₪1,749.85; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostMouse
Host / source
Mouse
Reactivity
Human, Mouse
Applications
Western blot Immunocytochemistry Immunohistochemistry
UniProt ID
O14786
Gene
NRP1
Target organism
Homo sapiens
Catalogue number
48067
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: Neuropilin-1 (NRP1) · Homo sapiens

Cell-surface receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. Mediates the chemorepulsant activity of semaphorins. Recognizes a C-end rule (CendR) motif R/KXXR/K on its ligands which causes cellular internalization and vascular leakage. It binds to semaphorin 3A, the PLGF-2 isoform of PGF, the VEGF165 isoform of VEGFA and VEGFB. Coexpression with KDR results in increased VEGF165 binding to KDR as well as increased chemotaxis. Regulates VEGF-induced angiogenesis.

Subcellular location: Secreted

Tissue specificity: The expression of isoforms 1 and 2 does not seem to overlap. Expressed in olfactory epithelium (at protein level). Expressed in fibroblasts (at protein level). Expressed by the blood vessels of different tissues. In the developing embryo it is found predominantly in the nervous system.

Sequence length: 923 aa · 103134 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.