
47774
PTGDR2 Antibody
PTGDR2 Antibody (catalogue number 47774) is a rabbit-derived primary antibody validated for Western blot, Immunohistochemistry, reactive with Human, Mouse, Rat samples. It targets Prostaglandin D2 receptor 2 (PTGDR2): Receptor for prostaglandin D2 (PGD2). Supplied as 100ul at ₪1,301.17; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.
- Host / source
- Rabbit
- Reactivity
- Human, Mouse, Rat
- Applications
- Western blot Immunohistochemistry
- UniProt ID
- Q9Y5Y4
- Gene
- PTGDR2
- Target organism
- Homo sapiens
- Catalogue number
- 47774
- Brand
- LABO Scientific
- Storage
- Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Target background
Target: Prostaglandin D2 receptor 2 (PTGDR2) · Homo sapiens
Receptor for prostaglandin D2 (PGD2). Coupled to the G(i)-protein. Receptor activation may result in pertussis toxin-sensitive decreases in cAMP levels and Ca(2+) mobilization. PI3K signaling is also implicated in mediating PTGDR2 effects. PGD2 induced receptor internalization. CRTH2 internalization can be regulated by diverse kinases such as, PKC, PKA, GRK2, GPRK5/GRK5 and GRK6. Receptor activation is responsible, at least in part, in immune regulation and allergic/inflammation responses
Subcellular location: Cell membrane
Tissue specificity: Widespread expression. High expression in stomach, small intestine, heart and thymus. Intermediate expression in colon, spinal cord and peripheral blood and low expression in brain, skeletal muscle and spleen. Expressed also on Th2- and Tc2- type cells, eosinophils and basophils
Sequence length: 395 aa · 43268 Da
Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Storage
- Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il