Loading...
SHTN1 Antibody

47695

SHTN1 Antibody

SHTN1 Antibody (catalogue number 47695) is a rabbit-derived primary antibody validated for Western blot, Immunohistochemistry, reactive with Human samples. It targets Shootin-1 (SHTN1): Involved in the generation of internal asymmetric signals required for neuronal polarization and neurite outgrowth. Supplied as 100ul at ₪1,301.17; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRabbit
Host / source
Rabbit
Reactivity
Human
Applications
Western blot Immunohistochemistry
UniProt ID
A0MZ66
Gene
SHTN1
Target organism
Homo sapiens
Catalogue number
47695
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: Shootin-1 (SHTN1) · Homo sapiens

Involved in the generation of internal asymmetric signals required for neuronal polarization and neurite outgrowth. Mediates netrin-1-induced F-actin-substrate coupling or 'clutch engagement' within the axon growth cone through activation of CDC42, RAC1 and PAK1-dependent signaling pathway, thereby converting the F-actin retrograde flow into traction forces, concomitantly with filopodium extension and axon outgrowth. Plays a role in cytoskeletal organization by regulating the subcellular localization of phosphoinositide 3-kinase (PI3K) activity at the axonal growth cone.

Subcellular location: Perikaryon; Cell projection, axon; Cell projection, growth cone; Cytoplasm, cytoskeleton; Cell projection, filopodium; Cell projection, lamellipodium

Sequence length: 631 aa · 71640 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.