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GSPT2 Antibody

47422

GSPT2 Antibody

GSPT2 Antibody (catalogue number 47422) is a rabbit-derived primary antibody validated for Western blot, Immunohistochemistry, reactive with Human, Mouse samples. It targets Eukaryotic peptide chain release factor GTP-binding subunit ERF3B (GSPT2): GTPase component of the eRF1-eRF3-GTP ternary complex, a ternary complex that mediates translation termination in response to the termination codons UAA, UAG and UGA. Supplied as 100ul at ₪1,301.17; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRabbit
Host / source
Rabbit
Reactivity
Human, Mouse
Applications
Western blot Immunohistochemistry
UniProt ID
Q8IYD1
Gene
GSPT2
Target organism
Homo sapiens
Catalogue number
47422
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: Eukaryotic peptide chain release factor GTP-binding subunit ERF3B (GSPT2) · Homo sapiens

GTPase component of the eRF1-eRF3-GTP ternary complex, a ternary complex that mediates translation termination in response to the termination codons UAA, UAG and UGA. GSPT2/ERF3B mediates ETF1/ERF1 delivery to stop codons: The eRF1-eRF3-GTP complex binds to a stop codon in the ribosomal A-site. GTP hydrolysis by GSPT2/ERF3B induces a conformational change that leads to its dissociation, permitting ETF1/ERF1 to accommodate fully in the A-site.

Subcellular location: Cytoplasm

Tissue specificity: Highly expressed in IUCC stage II colorectal cancer (CRC)

Sequence length: 628 aa · 68883 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.