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DUX4 Antibody

47085

DUX4 Antibody

DUX4 Antibody (catalogue number 47085) is a rabbit-derived primary antibody validated for Immunohistochemistry, reactive with Human samples. It targets Double homeobox protein 4 (DUX4): Transcription factor that is selectively and transiently expressed in cleavage-stage embryos. Supplied as 100ul at ₪1,301.17; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRabbit
Host / source
Rabbit
Reactivity
Human
Applications
Immunohistochemistry
UniProt ID
Q9UBX2
Gene
DUX4
Target organism
Homo sapiens
Catalogue number
47085
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: Double homeobox protein 4 (DUX4) · Homo sapiens

Transcription factor that is selectively and transiently expressed in cleavage-stage embryos. Binds to double-stranded DNA elements with the consensus sequence 5'-TAATCTAATCA-3'. Binds to chromatin containing histone H3 acetylated at 'Lys-27' (H3K27ac) and promotes deacetylation of H3K27ac. In parallel, binds to chromatin that lacks histone H3 acetylation at 'Lys-27' (H3K27ac) and recruits EP300 and CREBBP to promote acetylation of histone H3 at 'Lys-27' at new sites.

Subcellular location: Nucleus; Cytoplasm

Tissue specificity: Isoform 1: Does not seem to be expressed in normal muscle, but is detected in muscle of individuals with FSHD, and also in testis (at protein level). Isoform 1: Does not seem to be expressed in normal muscle, but in muscle of individuals with FSHD, where it may be toxic to cells.

Sequence length: 424 aa · 44940 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.