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GCK/GLK Polyclonal Antibody

46910

GCK/GLK Polyclonal Antibody

GCK/GLK Polyclonal Antibody (catalogue number 46910) is a rabbit-derived primary antibody validated for Western blot, reactive with Hu Rt samples. It targets Mitogen-activated protein kinase kinase kinase kinase 2 (MAP4K2): Serine/threonine-protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Supplied in 2 pack sizes, from 50ul at ₪893.28 to 100ul at ₪1,301.17; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRabbit
Host / source
Rabbit
Reactivity
Hu Rt
Applications
Western blot
UniProt ID
Q12851
Gene
MAP4K2
Target organism
Homo sapiens
Catalogue number
46910
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: Mitogen-activated protein kinase kinase kinase kinase 2 (MAP4K2) · Homo sapiens

Serine/threonine-protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Acts as a MAPK kinase kinase kinase (MAP4K) and is an upstream activator of the stress-activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) signaling pathway and to a lesser extent of the p38 MAPKs signaling pathway. Required for the efficient activation of JNKs by TRAF6-dependent stimuli, including pathogen-associated molecular patterns (PAMPs) such as polyinosine-polycytidine (poly(IC)), lipopolysaccharides (LPS), lipid A, peptidoglycan (PGN), or bacterial flagellin.

Subcellular location: Cytoplasm; Basolateral cell membrane; Golgi apparatus membrane

Tissue specificity: Highly expressed in germinal center but not mantle zone B-cells. Also expressed in lung, brain and placenta and at lower levels in other tissues examined

Sequence length: 820 aa · 91556 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.