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NNT Polyclonal Antibody

46837

NNT Polyclonal Antibody

NNT Polyclonal Antibody (catalogue number 46837) is a rabbit-derived primary antibody validated for Immunohistochemistry, reactive with Hu Ms Rt samples. It targets Cardiotrophin-like cytokine factor 1 (CLCF1): Functions as a cytokine, either alone or by forming a stable complex with soluble CRLF1 or CNTFR. Supplied in 2 pack sizes, from 50ul at ₪893.28 to 100ul at ₪1,301.17; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRabbit
Host / source
Rabbit
Reactivity
Hu Ms Rt
Applications
Immunohistochemistry
UniProt ID
Q9UBD9
Gene
CLCF1
Target organism
Homo sapiens
Catalogue number
46837
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: Cardiotrophin-like cytokine factor 1 (CLCF1) · Homo sapiens

Functions as a cytokine, either alone or by forming a stable complex with soluble CRLF1 or CNTFR. Binds to CNTFR complex (CNTFR, IL6ST/gp130, LIFR) or can signal via trans-signaling using soluble CNTFR subunits. Mechanistically, ligand binding to CNTFR, induces dimerization of the IL6ST/gp130 and LIFR, which activates JAK tyrosine kinases (JAK1 or JAK2 and to lesser extent TYK2) bound to their intracellular domains. These kinases subsequently phosphorylate IL6ST/gp130 and LIFR.

Subcellular location: Secreted

Tissue specificity: Expressed predominantly in lymph nodes, spleen, peripheral blood lymphocytes, bone marrow, and fetal liver

Sequence length: 225 aa · 25176 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.