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WDFY3 Antibody

46709

WDFY3 Antibody

WDFY3 Antibody (catalogue number 46709) is a rabbit-derived primary antibody validated for WB IHC, reactive with Human samples. It targets WD repeat and FYVE domain-containing protein 3 (WDFY3): Required for selective macroautophagy (aggrephagy). Supplied as 100ul at ₪1,301.17; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRabbit
Host / source
Rabbit
Reactivity
Human
Applications
WB IHC
UniProt ID
Q8IZQ1
Gene
WDFY3
Target organism
Homo sapiens
Catalogue number
46709
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: WD repeat and FYVE domain-containing protein 3 (WDFY3) · Homo sapiens

Required for selective macroautophagy (aggrephagy). Acts as an adapter protein by linking specific proteins destined for degradation to the core autophagic machinery members, such as the ATG5-ATG12-ATG16L E3-like ligase, SQSTM1 and LC3. Along with p62/SQSTM1, involved in the formation and autophagic degradation of cytoplasmic ubiquitin-containing inclusions (p62 bodies, ALIS/aggresome-like induced structures). Along with SQSTM1, required to recruit ubiquitinated proteins to PML bodies in the nucleus. Important for normal brain development.

Subcellular location: Nucleus membrane; Cytoplasm, cytosol; Nucleus, PML body; Membrane; Perikaryon; Cell projection, axon

Tissue specificity: Expressed in osteoclast and their mononuclear precursors (at protein level)

Sequence length: 3526 aa · 395258 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.