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USP12 Antibody

46696

USP12 Antibody

USP12 Antibody (catalogue number 46696) is a rabbit-derived primary antibody validated for WB IHC, reactive with Hu Ms samples. It targets Ubiquitin carboxyl-terminal hydrolase 12 (USP12): Deubiquitinating enzyme that plays various roles in the regulation of the immune response and inflammation. Supplied as 100ul at ₪1,301.17; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRabbit
Host / source
Rabbit
Reactivity
Hu Ms
Applications
WB IHC
UniProt ID
O75317
Gene
USP12
Target organism
Homo sapiens
Catalogue number
46696
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: Ubiquitin carboxyl-terminal hydrolase 12 (USP12) · Homo sapiens

Deubiquitinating enzyme that plays various roles in the regulation of the immune response and inflammation. During TCR engagement and activation, translocates into the cytoplasm and deubiquitinates its substrates LAT and TRAT1 and prevents their lysosome-dependent degradation to stabilize the TCR signaling complex at the plasma membrane. Plays an essential role in the selective LPS-induced macrophage response through the activation of NF-kappa-B pathway. In addition, promotes that antiviral immune response through targeting DNA sensor IFI16 to inhibit its proteasome-dependent degradation.

Subcellular location: Nucleus; Cytoplasm; Cell membrane

Sequence length: 370 aa · 42858 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.