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MBD2-b Antibody

46610

MBD2-b Antibody

MBD2-b Antibody (catalogue number 46610) is a rabbit-derived primary antibody validated for Immunohistochemistry, reactive with Human samples. It targets Methyl-CpG-binding domain protein 2 (MBD2): Binds CpG islands in promoters where the DNA is methylated at position 5 of cytosine within CpG dinucleotides. Supplied as 100ul at ₪1,301.17; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRabbit
Host / source
Rabbit
Reactivity
Human
Applications
Immunohistochemistry
UniProt ID
Q9UBB5
Gene
MBD2
Target organism
Homo sapiens
Catalogue number
46610
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: Methyl-CpG-binding domain protein 2 (MBD2) · Homo sapiens

Binds CpG islands in promoters where the DNA is methylated at position 5 of cytosine within CpG dinucleotides. Binds hemimethylated DNA as well. Recruits histone deacetylases and DNA methyltransferases to chromatin. Acts as a component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin. Acts as a transcriptional repressor and plays a role in gene silencing. Functions as a scaffold protein, targeting GATAD2A and GATAD2B to chromatin to promote repression. May enhance the activation of some unmethylated cAMP-responsive promoters

Subcellular location: Nucleus; Chromosome

Tissue specificity: Highly expressed in brain, heart, kidney, stomach, testis and placenta

Sequence length: 411 aa · 43255 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.