45953
HECW1 Antibody
HECW1 Antibody (catalogue number 45953) is a rabbit-derived primary antibody validated for Western blot, reactive with Human samples. It targets E3 ubiquitin-protein ligase HECW1 (HECW1): E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent degradation of DVL1. Supplied in 2 pack sizes, from 50ul at ₪893.28 to 100ul at ₪1,301.17; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.
- Host / source
- Rabbit
- Reactivity
- Human
- Applications
- Western blot
- UniProt ID
- Q76N89
- Gene
- HECW1
- Target organism
- Homo sapiens
- Catalogue number
- 45953
- Brand
- LABO Scientific
- Storage
- Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Target background
Target: E3 ubiquitin-protein ligase HECW1 (HECW1) · Homo sapiens
E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent degradation of DVL1. Also targets the mutant SOD1 protein involved in familial amyotrophic lateral sclerosis (FALS). Forms cytotoxic aggregates with DVL1, SSR3 and mutant SOD1 that lead to motor neuron death in FALS
Subcellular location: Cytoplasm
Tissue specificity: Predominantly expressed in neurons of adult and fetal brain. Weakly expressed in the kidney
Sequence length: 1606 aa · 179554 Da
Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Storage
- Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il