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Lrp2 / Megalin Antibody

45026

Lrp2 / Megalin Antibody

Lrp2 / Megalin Antibody (catalogue number 45026) is a rabbit-derived primary antibody validated for Western blot, IH, reactive with Hu Ms Rt samples. It targets Low-density lipoprotein receptor-related protein 2 (LRP2): Multiligand endocytic receptor. Supplied in 2 pack sizes, from 50ul at ₪893.28 to 100ul at ₪1,301.17; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRabbit
Host / source
Rabbit
Reactivity
Hu Ms Rt
Applications
Western blot IH
UniProt ID
P98164
Gene
LRP2
Target organism
Homo sapiens
Catalogue number
45026
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: Low-density lipoprotein receptor-related protein 2 (LRP2) · Homo sapiens

Multiligand endocytic receptor. Acts together with CUBN to mediate endocytosis of high-density lipoproteins. Mediates receptor-mediated uptake of polybasic drugs such as aprotinin, aminoglycosides and polymyxin B. In the kidney, mediates the tubular uptake and clearance of leptin. Also mediates transport of leptin across the blood-brain barrier through endocytosis at the choroid plexus epithelium. Endocytosis of leptin in neuronal cells is required for hypothalamic leptin signaling and leptin-mediated regulation of feeding and body weight.

Subcellular location: Apical cell membrane; Endosome lumen; Membrane, coated pit; Cell projection, dendrite; Cell projection, axon

Tissue specificity: Expressed in first and third trimester cytotrophoblasts in the placenta (at protein level). Absorptive epithelia, including renal proximal tubules

Sequence length: 4655 aa · 521958 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.