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Cytochrome P450 11B2 Antibody

44509

Cytochrome P450 11B2 Antibody

Cytochrome P450 11B2 Antibody (catalogue number 44509) is a rabbit-derived primary antibody validated for Western blot, reactive with Hu Ms Rt samples. It targets Cytochrome P450 11B2, mitochondrial (CYP11B2): A cytochrome P450 monooxygenase that catalyzes the biosynthesis of aldosterone, the main mineralocorticoid in the human body responsible for salt and water homeostasis, thus involved in blood pressure regulation, arterial hypertension, and the development of… Supplied in 2 pack sizes, from 50ul at ₪893.28 to 100ul at ₪1,301.17; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRabbit
Host / source
Rabbit
Reactivity
Hu Ms Rt
Applications
Western blot
UniProt ID
P19099
Gene
CYP11B2
Target organism
Homo sapiens
Catalogue number
44509
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: Cytochrome P450 11B2, mitochondrial (CYP11B2) · Homo sapiens

A cytochrome P450 monooxygenase that catalyzes the biosynthesis of aldosterone, the main mineralocorticoid in the human body responsible for salt and water homeostasis, thus involved in blood pressure regulation, arterial hypertension, and the development of heart failure. Catalyzes three sequential oxidative reactions of 11-deoxycorticosterone (21-hydroxyprogesterone), namely 11-beta hydroxylation, followed by two successive oxidations at C18 yielding 18-hydroxy and then 18-oxo intermediates (that would not leave the enzyme active site during the consecutive hydroxylation reactions), ending w…

Subcellular location: Mitochondrion inner membrane

Tissue specificity: Expressed sporadically in the zona glomerulosa (zG) of the adrenal cortex (conventional zonation), as well as in aldosterone-producing cell clusters (APCCs) composed of morphological zG cells in contact with the capsule (variegated zonation)

Sequence length: 503 aa · 57560 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.