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GLI2 Antibody

43461

GLI2 Antibody

GLI2 Antibody (catalogue number 43461) is a rabbit-derived primary antibody validated for Immunohistochemistry, reactive with Hu Ms samples. It targets Transcription activator GLI2 (GLI2): Transcription factor that acts as a key effector of the smoothened signaling pathway, and which plays a role in skeleton development. Supplied as 100ul at ₪1,301.17; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRabbit
Host / source
Rabbit
Reactivity
Hu Ms
Applications
Immunohistochemistry
UniProt ID
P10070
Gene
GLI2
Target organism
Homo sapiens
Catalogue number
43461
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: Transcription activator GLI2 (GLI2) · Homo sapiens

Transcription factor that acts as a key effector of the smoothened signaling pathway, and which plays a role in skeleton development. Specifically binds to the minimal GLI-consensus sequence 5'-GACCACCCA-3' to activate or repress the expression of target genes. Functions both as a transcriptional activator and repressor: the full-length GLI2 form (Transcription activator GLI2) acts as a transcription activator following smoothened activation, while the Transcription repressor GLI2R, which is generated in absence of smoothened, acts as a transcription repressor.

Subcellular location: Nucleus; Cytoplasm; Cell projection, cilium

Tissue specificity: Expressed in breast cancers (at protein level). Isoform 1 and isoform 4 are expressed in HTLV-1-infected T-cell lines (at protein level). Isoform 1 and isoform 2 are strongly expressed in HTLV-1-infected T-cell lines. Isoform 3 and isoform 4 are weakly expressed in HTLV-1-infected T-cell lines

Sequence length: 1586 aa · 167783 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.