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DDX58 Antibody

43258

DDX58 Antibody

DDX58 Antibody (catalogue number 43258) is a rabbit-derived primary antibody validated for Immunohistochemistry, reactive with Human samples. It targets Antiviral innate immune response receptor RIG-I (RIGI): Innate immune receptor that senses cytoplasmic viral nucleic acids and activates a downstream signaling cascade leading to the production of type I interferons and pro-inflammatory cytokines. Supplied as 100ul at ₪1,301.17; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRabbit
Host / source
Rabbit
Reactivity
Human
Applications
Immunohistochemistry
UniProt ID
O95786
Gene
RIGI
Target organism
Homo sapiens
Catalogue number
43258
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: Antiviral innate immune response receptor RIG-I (RIGI) · Homo sapiens

Innate immune receptor that senses cytoplasmic viral nucleic acids and activates a downstream signaling cascade leading to the production of type I interferons and pro-inflammatory cytokines. Forms a ribonucleoprotein complex with viral RNAs on which it homooligomerizes to form filaments. The homooligomerization allows the recruitment of RNF135 an E3 ubiquitin-protein ligase that activates and amplifies the RIG-I-mediated antiviral signaling in an RNA length-dependent manner through ubiquitination-dependent and -independent mechanisms.

Subcellular location: Cytoplasm; Cell projection, ruffle membrane; Cytoplasm, cytoskeleton; Cell junction, tight junction

Tissue specificity: Present in vascular smooth cells (at protein level)

Sequence length: 925 aa · 106600 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.