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DNASE1 Antibody

42716

DNASE1 Antibody

DNASE1 Antibody (catalogue number 42716) is a rabbit-derived primary antibody validated for Immunohistochemistry, reactive with Human samples. It targets Deoxyribonuclease-1 (DNASE1): Serum endocuclease secreted into body fluids by a wide variety of exocrine and endocrine organs. Supplied as 100ul at ₪1,301.17; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRabbit
Host / source
Rabbit
Reactivity
Human
Applications
Immunohistochemistry
UniProt ID
P24855
Gene
DNASE1
Target organism
Homo sapiens
Catalogue number
42716
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: Deoxyribonuclease-1 (DNASE1) · Homo sapiens

Serum endocuclease secreted into body fluids by a wide variety of exocrine and endocrine organs. Expressed by non-hematopoietic tissues and preferentially cleaves protein-free DNA. Among other functions, seems to be involved in cell death by apoptosis. Binds specifically to G-actin and blocks actin polymerization. Together with DNASE1L3, plays a key role in degrading neutrophil extracellular traps (NETs). NETs are mainly composed of DNA fibers and are released by neutrophils to bind pathogens during inflammation.

Subcellular location: Secreted; Zymogen granule; Nucleus envelope

Tissue specificity: Principally in tissues of the digestive system. Highest levels found in urine, but also relatively abundant in semen and saliva

Sequence length: 282 aa · 31434 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.