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WD repeat-containing protein 54 Polyclonal Antibody

42687

WD repeat-containing protein 54 Polyclonal Antibody

WD repeat-containing protein 54 Polyclonal Antibody (catalogue number 42687) is a rabbit-derived primary antibody validated for Western blot, reactive with Human samples. It targets WD repeat-containing protein 54 (WDR54): Plays a role in the adhesion and fusion of the sperm-oocyte membrane through its interactions with IZUMO1 and IZUMO1R/JUNO. Supplied as 100μg at ₪1,590.78; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRabbit
Host / source
Rabbit
Reactivity
Human
Applications
Western blot
UniProt ID
Q9H977
Gene
WDR54
Target organism
Homo sapiens
Catalogue number
42687
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: WD repeat-containing protein 54 (WDR54) · Homo sapiens

Plays a role in the adhesion and fusion of the sperm-oocyte membrane through its interactions with IZUMO1 and IZUMO1R/JUNO. When cross-linked to form dimers and trimers, it has a regulatory effect on ERK signaling pathway activity in response to EGF stimulation. Colocalizes with the EGF receptor in WDR54-specific vesicle where it sustains the internalization and controls the degradation of the EGF receptor after EGF stimulation

Subcellular location: Vesicle; Cytoplasm; Cell membrane

Tissue specificity: Expressed in epithelial cells (at protein level). Isoform 3 expression is highly increased in colorectal cancer cells

Sequence length: 334 aa · 35891 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.