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ptxA Polyclonal Antibody

42634

ptxA Polyclonal Antibody

ptxA Polyclonal Antibody (catalogue number 42634) is a rabbit-derived primary antibody validated for Western blot, reactive with Bordetella pertussis samples. It targets Pertussis toxin subunit 1 (ptxA): S1 is an NAD-dependent ADP-ribosyltransferase, which plays a crucial role in the pathogenesis of B.pertussis causing disruption of normal host cellular regulation. Supplied as 100μg at ₪1,590.78; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRabbit
Host / source
Rabbit
Reactivity
Bordetella pertussis
Applications
Western blot
UniProt ID
P04977
Gene
ptxA
Target organism
Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251)
Catalogue number
42634
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: Pertussis toxin subunit 1 (ptxA) · Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251)

S1 is an NAD-dependent ADP-ribosyltransferase, which plays a crucial role in the pathogenesis of B.pertussis causing disruption of normal host cellular regulation. It catalyzes the ADP-ribosylation of a cysteine in the alpha subunit of host heterotrimeric G proteins. In the absence of G proteins it also catalyzes the cleavage of NAD(+) into ADP-ribose and nicotinamide. It irreversibly uncouples the G-alpha GTP-binding proteins from their membrane receptors

Subcellular location: Secreted

Sequence length: 269 aa · 29974 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.