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Hrs Polyclonal Antibody

41566

Hrs Polyclonal Antibody

Hrs Polyclonal Antibody (catalogue number 41566) is a rabbit-derived primary antibody validated for WB ELISA, reactive with Hu Ms Rt samples. It targets Hepatocyte growth factor-regulated tyrosine kinase substrate (HGS): Involved in intracellular signal transduction mediated by cytokines and growth factors. Supplied in 2 pack sizes, from 50ul at ₪893.28 to 100ul at ₪1,301.17; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRabbit
Host / source
Rabbit
Reactivity
Hu Ms Rt
Applications
WB ELISA
UniProt ID
O14964
Gene
HGS
Target organism
Homo sapiens
Catalogue number
41566
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: Hepatocyte growth factor-regulated tyrosine kinase substrate (HGS) · Homo sapiens

Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin-coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (ESCRT-0 complex).

Subcellular location: Cytoplasm; Early endosome membrane; Endosome, multivesicular body membrane

Tissue specificity: Ubiquitous expression in adult and fetal tissues with higher expression in testis and peripheral blood leukocytes

Sequence length: 777 aa · 86192 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.