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Siah/2 Polyclonal Antibody

41434

Siah/2 Polyclonal Antibody

Siah/2 Polyclonal Antibody (catalogue number 41434) is a rabbit-derived primary antibody validated for WB IHC IF ELISA, reactive with Hu Ms Rt samples. It targets E3 ubiquitin-protein ligase SIAH1 (SIAH1): E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. Supplied in 2 pack sizes, from 50ul at ₪893.28 to 100ul at ₪1,301.17; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRabbit
Host / source
Rabbit
Reactivity
Hu Ms Rt
Applications
WB IHC IF ELISA
UniProt ID
Q8IUQ4
Gene
SIAH1
Target organism
Homo sapiens
Catalogue number
41434
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: E3 ubiquitin-protein ligase SIAH1 (SIAH1) · Homo sapiens

E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates E3 ubiquitin ligase activity either through direct binding to substrates or by functioning as the essential RING domain subunit of larger E3 complexes.

Subcellular location: Cytoplasm; Nucleus

Tissue specificity: Widely expressed at a low level. Down-regulated in advanced hepatocellular carcinomas

Sequence length: 282 aa · 31123 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.