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Rock-2 Polyclonal Antibody

41415

Rock-2 Polyclonal Antibody

Rock-2 Polyclonal Antibody (catalogue number 41415) is a rabbit-derived primary antibody validated for WB ELISA, reactive with Hu Ms Rt Mk samples. It targets Rho-associated protein kinase 2 (ROCK2): Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. Supplied in 2 pack sizes, from 50ul at ₪893.28 to 100ul at ₪1,301.17; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRabbit
Host / source
Rabbit
Reactivity
Hu Ms Rt Mk
Applications
WB ELISA
UniProt ID
O75116
Gene
ROCK2
Target organism
Homo sapiens
Catalogue number
41415
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: Rho-associated protein kinase 2 (ROCK2) · Homo sapiens

Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. Involved in regulation of smooth muscle contraction, actin cytoskeleton organization, stress fiber and focal adhesion formation, neurite retraction, cell adhesion and motility via phosphorylation of ADD1, BRCA2, CNN1, EZR, DPYSL2, EP300, MSN, MYL9/MLC2, NPM1, RDX, PPP1R12A and VIM. Phosphorylates SORL1 and IRF4. Acts as a negative regulator of VEGF-induced angiogenic endothelial cell activation. Positively regulates the activation of p42/MAPK1-p44/MAPK3 and of p90RSK/RPS6KA1 during myogenic differentiation.

Subcellular location: Cytoplasm; Cell membrane; Nucleus; Cytoplasm, cytoskeleton, microtubule organizing center, centrosome

Tissue specificity: Expressed in the brain (at protein level)

Sequence length: 1388 aa · 160900 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.