
40351
UACA Antibody
UACA Antibody (catalogue number 40351) is a rabbit-derived primary antibody validated for Immunohistochemistry, reactive with Human samples. It targets Uveal autoantigen with coiled-coil domains and ankyrin repeats (UACA): Regulates APAF1 expression and plays an important role in the regulation of stress-induced apoptosis. Supplied as 100ul at ₪1,301.17; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.
- Host / source
- Rabbit
- Reactivity
- Human
- Applications
- Immunohistochemistry
- UniProt ID
- Q9BZF9
- Gene
- UACA
- Target organism
- Homo sapiens
- Catalogue number
- 40351
- Brand
- LABO Scientific
- Storage
- Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Target background
Target: Uveal autoantigen with coiled-coil domains and ankyrin repeats (UACA) · Homo sapiens
Regulates APAF1 expression and plays an important role in the regulation of stress-induced apoptosis. Promotes apoptosis by regulating three pathways, apoptosome up-regulation, LGALS3/galectin-3 down-regulation and NF-kappa-B inactivation. Regulates the redistribution of APAF1 into the nucleus after proapoptotic stress. Down-regulates the expression of LGALS3 by inhibiting NFKB1
Subcellular location: Nucleus; Cytoplasm; Cytoplasm, cytoskeleton
Tissue specificity: Highly expressed in skeletal muscle, heart, kidney and pancreas. Expressed in choroid, retina and epidermal melanocytes. Expressed in eye muscles and thyroid follicular cells
Sequence length: 1416 aa · 162505 Da
Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Storage
- Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il