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TRIM63 antibody

38580

TRIM63 antibody

TRIM63 antibody (catalogue number 38580) is a rabbit-derived primary antibody validated for Western blot, Immunohistochemistry, Immunofluorescence, reactive with Human, Mouse, Rat samples. It targets E3 ubiquitin-protein ligase TRIM63 (TRIM63): E3 ubiquitin ligase. Mediates the ubiquitination and subsequent proteasomal degradation of CKM, GMEB1 and HIBADH. Supplied in 2 pack sizes, from 50ul at ₪1,260.38 to 100ul at ₪1,790.64; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRabbit
Host / source
Rabbit
Reactivity
Human, Mouse, Rat
Applications
Western blot Immunohistochemistry Immunofluorescence
UniProt ID
Q969Q1
Gene
TRIM63
Target organism
Homo sapiens
Catalogue number
38580
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: E3 ubiquitin-protein ligase TRIM63 (TRIM63) · Homo sapiens

E3 ubiquitin ligase. Mediates the ubiquitination and subsequent proteasomal degradation of CKM, GMEB1 and HIBADH. Regulates the proteasomal degradation of muscle proteins under amino acid starvation, where muscle protein is catabolized to provide other organs with amino acids. Inhibits de novo skeletal muscle protein synthesis under amino acid starvation. Regulates proteasomal degradation of cardiac troponin I/TNNI3 and probably of other sarcomeric-associated proteins. May play a role in striated muscle atrophy and hypertrophy by regulating an anti-hypertrophic PKC-mediated signaling pathway.

Subcellular location: Cytoplasm; Nucleus; Cytoplasm, myofibril, sarcomere, M line; Cytoplasm, myofibril, sarcomere, Z line

Tissue specificity: Muscle specific. Selectively expressed in heart and skeletal muscle. Also expressed in the iris

Sequence length: 353 aa · 40248 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.