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HACE1 Antibody

37612

HACE1 Antibody

HACE1 Antibody (catalogue number 37612) is a rabbit-derived primary antibody validated for Immunohistochemistry, reactive with Hu Ms Rt samples. It targets E3 ubiquitin-protein ligase HACE1 (HACE1): E3 ubiquitin-protein ligase involved in Golgi membrane fusion and regulation of small GTPases. Supplied as 100ul at ₪1,301.17; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRabbit
Host / source
Rabbit
Reactivity
Hu Ms Rt
Applications
Immunohistochemistry
UniProt ID
Q8IYU2
Gene
HACE1
Target organism
Homo sapiens
Catalogue number
37612
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: E3 ubiquitin-protein ligase HACE1 (HACE1) · Homo sapiens

E3 ubiquitin-protein ligase involved in Golgi membrane fusion and regulation of small GTPases. Acts as a regulator of Golgi membrane dynamics during the cell cycle: recruited to Golgi membrane by Rab proteins and regulates postmitotic Golgi membrane fusion. Acts by mediating ubiquitination during mitotic Golgi disassembly, ubiquitination serving as a signal for Golgi reassembly later, after cell division. Specifically binds GTP-bound RAC1, mediating ubiquitination and subsequent degradation of active RAC1, thereby playing a role in host defense against pathogens.

Subcellular location: Golgi apparatus, Golgi stack membrane; Cytoplasm; Endoplasmic reticulum

Tissue specificity: Expressed in multiple tissues including heart, brain and kidney

Sequence length: 909 aa · 102342 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.