Loading...
CACNA1C Antibody

37451

CACNA1C Antibody

CACNA1C Antibody (catalogue number 37451) is a rabbit-derived primary antibody validated for Immunohistochemistry, reactive with Human samples. It targets Voltage-dependent L-type calcium channel subunit alpha-1C (CACNA1C): Pore-forming, alpha-1C subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents. Supplied as 100ul at ₪1,301.17; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRabbit
Host / source
Rabbit
Reactivity
Human
Applications
Immunohistochemistry
UniProt ID
Q13936
Gene
CACNA1C
Target organism
Homo sapiens
Catalogue number
37451
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: Voltage-dependent L-type calcium channel subunit alpha-1C (CACNA1C) · Homo sapiens

Pore-forming, alpha-1C subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents. Mediates influx of calcium ions into the cytoplasm, and thereby triggers calcium release from the sarcoplasm. Plays an important role in excitation-contraction coupling in the heart. Required for normal heart development and normal regulation of heart rhythm. Required for normal contraction of smooth muscle cells in blood vessels and in the intestine. Essential for normal blood pressure regulation via its role in the contraction of arterial smooth muscle cells.

Subcellular location: Cell membrane; Cell membrane, sarcolemma; Perikaryon; Postsynaptic density membrane; Cell projection, dendrite; Cell membrane, sarcolemma, T-tubule

Tissue specificity: Detected throughout the brain, including hippocampus, cerebellum and amygdala, throughout the heart and vascular system, including ductus arteriosus, in urinary bladder, and in retina and sclera in the eye. Expressed in brain, heart, jejunum, ovary, pancreatic beta-cells and vascular smooth muscle.

Sequence length: 2221 aa · 248977 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.