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DXT1 Antibody

36825

DXT1 Antibody

DXT1 Antibody (catalogue number 36825) is a rabbit-derived primary antibody validated for Immunohistochemistry, reactive with Hu Ms samples. It targets E3 ubiquitin-protein ligase DTX1 (DTX1): E3 ubiquitin-protein ligase that mediates ubiquitination and proteasomal degradation of MEKK1, thereby modulating signaling pathways involved in cell fate determination. Supplied as 100ul at ₪1,301.17; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRabbit
Host / source
Rabbit
Reactivity
Hu Ms
Applications
Immunohistochemistry
UniProt ID
Q86Y01
Gene
DTX1
Target organism
Homo sapiens
Catalogue number
36825
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: E3 ubiquitin-protein ligase DTX1 (DTX1) · Homo sapiens

E3 ubiquitin-protein ligase that mediates ubiquitination and proteasomal degradation of MEKK1, thereby modulating signaling pathways involved in cell fate determination. Regulates the Notch signaling pathway, acting predominantly as a positive regulator but functioning as a context-dependent negative regulator in specific developmental or cellular settings. Mediates the antineural activity of Notch signaling, likely by inhibiting transcriptional activation mediated by MATCH1.

Subcellular location: Cytoplasm; Nucleus; Endosome

Tissue specificity: Widely expressed. Strongly expressed in blood vessel. Also expressed in embryonic nervous system, pancreas, lung, adrenal gland, digestive tube and muscles. Expressed in MZB cells and developing B- and T-cells

Sequence length: 620 aa · 67368 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.