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PLEKHG6 Antibody

36627

PLEKHG6 Antibody

PLEKHG6 Antibody (catalogue number 36627) is a rabbit-derived primary antibody validated for WB IHC, reactive with Human samples. It targets Pleckstrin homology domain-containing family G member 6 (PLEKHG6): Guanine nucleotide exchange factor activating the small GTPase RHOA, which, in turn, induces myosin filament formation. Supplied as 100ul at ₪1,301.17; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRabbit
Host / source
Rabbit
Reactivity
Human
Applications
WB IHC
UniProt ID
Q3KR16
Gene
PLEKHG6
Target organism
Homo sapiens
Catalogue number
36627
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: Pleckstrin homology domain-containing family G member 6 (PLEKHG6) · Homo sapiens

Guanine nucleotide exchange factor activating the small GTPase RHOA, which, in turn, induces myosin filament formation. Also activates RHOG. Does not activate RAC1, or to a much lower extent than RHOA and RHOG. Part of a functional unit, involving PLEKHG6, MYH10 and RHOA, at the cleavage furrow to advance furrow ingression during cytokinesis. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with EZR, required for normal macropinocytosis

Subcellular location: Cell projection, microvillus; Cytoplasm, cytoskeleton, spindle; Cytoplasm, cytoskeleton, spindle pole; Cleavage furrow

Tissue specificity: Highest expression in the placenta. Low levels in small intestine, lung, liver, kidney, thymus and heart

Sequence length: 790 aa · 88960 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.