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KLHL2 Antibody

36573

KLHL2 Antibody

KLHL2 Antibody (catalogue number 36573) is a rabbit-derived primary antibody validated for WB IHC, reactive with Human samples. It targets Kelch-like protein 2 (KLHL2): Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that mediates the ubiquitination of target proteins, such as NPTXR, WNK1, WNK3 and WNK4, leading most often to their proteasomal degradation. Supplied as 100ul at ₪1,301.17; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRabbit
Host / source
Rabbit
Reactivity
Human
Applications
WB IHC
UniProt ID
O95198
Gene
KLHL2
Target organism
Homo sapiens
Catalogue number
36573
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: Kelch-like protein 2 (KLHL2) · Homo sapiens

Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that mediates the ubiquitination of target proteins, such as NPTXR, WNK1, WNK3 and WNK4, leading most often to their proteasomal degradation. The BCR(KLHL2) complex catalyzes ubiquitination and degradation of NPTXR. Responsible for degradative ubiquitination of the WNK kinases WNK1, WNK3 and WNK4. Plays a role in the reorganization of the actin cytoskeleton. Promotes growth of cell projections in oligodendrocyte precursors

Subcellular location: Cytoplasm, cytoskeleton; Cell projection, ruffle; Cell projection; Cell projection, lamellipodium; Cytoplasm, cytosol

Tissue specificity: Ubiquitous. Detected throughout the brain

Sequence length: 593 aa · 65975 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.