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EDN1 Antibody

35735

EDN1 Antibody

EDN1 Antibody (catalogue number 35735) is a rabbit-derived primary antibody validated for Immunohistochemistry, reactive with Human samples. It targets Endothelin-1 (EDN1): Endothelins are endothelium-derived vasoconstrictor peptides. Supplied as 100ul at ₪1,301.17; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRabbit
Host / source
Rabbit
Reactivity
Human
Applications
Immunohistochemistry
UniProt ID
P05305
Gene
EDN1
Target organism
Homo sapiens
Catalogue number
35735
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: Endothelin-1 (EDN1) · Homo sapiens

Endothelins are endothelium-derived vasoconstrictor peptides. Probable ligand for G protein-coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells. Also binds the DEAR/FBXW7-AS1 receptor. Promotes mesenteric arterial wall remodeling via activation of ROCK signaling and subsequent colocalization of NFATC3 with F-actin filaments. NFATC3 then translocates to the nucleus where it subsequently promotes the transcription of the smooth muscle hypertrophy and differentiation marker ACTA2

Subcellular location: Secreted

Tissue specificity: Expressed in lung, placental stem villi vessels and in cultured placental vascular smooth muscle cells

Sequence length: 212 aa · 24425 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.