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SESN1 Antibody

35038

SESN1 Antibody

SESN1 Antibody (catalogue number 35038) is a rabbit-derived primary antibody validated for WB IHC, reactive with Hu Rt samples. It targets Sestrin-1 (SESN1): Functions as an intracellular leucine sensor that negatively regulates the TORC1 signaling pathway through the GATOR complex. Supplied in 2 pack sizes, from 50ul at ₪893.28 to 100ul at ₪1,301.17; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRabbit
Host / source
Rabbit
Reactivity
Hu Rt
Applications
WB IHC
UniProt ID
Q9Y6P5
Gene
SESN1
Target organism
Homo sapiens
Catalogue number
35038
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: Sestrin-1 (SESN1) · Homo sapiens

Functions as an intracellular leucine sensor that negatively regulates the TORC1 signaling pathway through the GATOR complex. In absence of leucine, binds the GATOR subcomplex GATOR2 and prevents TORC1 signaling. Binding of leucine to SESN2 disrupts its interaction with GATOR2 thereby activating the TORC1 signaling pathway. This stress-inducible metabolic regulator may also play a role in protection against oxidative and genotoxic stresses.

Subcellular location: Nucleus; Cytoplasm

Tissue specificity: Widely expressed

Sequence length: 492 aa · 56557 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.