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MEKKK 4 Antibody

33638

MEKKK 4 Antibody

MEKKK 4 Antibody (catalogue number 33638) is a rabbit-derived primary antibody validated for WB IF, reactive with Hu Ms samples. It targets Mitogen-activated protein kinase kinase kinase kinase 4 (MAP4K4): Serine/threonine kinase that plays a role in the response to environmental stress and cytokines such as TNF. Supplied in 2 pack sizes, from 50ul at ₪893.28 to 100ul at ₪1,301.17; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRabbit
Host / source
Rabbit
Reactivity
Hu Ms
Applications
WB IF
UniProt ID
O95819
Gene
MAP4K4
Target organism
Homo sapiens
Catalogue number
33638
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: Mitogen-activated protein kinase kinase kinase kinase 4 (MAP4K4) · Homo sapiens

Serine/threonine kinase that plays a role in the response to environmental stress and cytokines such as TNF. Appears to act upstream of the JUN N-terminal pathway. Activator of the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. MAP4Ks act in parallel to and are partially redundant with STK3/MST2 and STK4/MST2 in the phosphorylation and activation of LATS1/2, and establish MAP4Ks as components of the expanded Hippo pathway. Phosphorylates SMAD1 on Thr-322

Subcellular location: Cytoplasm

Tissue specificity: Widely expressed. Isoform 5 is abundant in the brain. Isoform 4 is predominant in the liver, skeletal muscle and placenta

Sequence length: 1239 aa · 142101 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.