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FBXO45 antibody

31960

FBXO45 antibody

FBXO45 antibody (catalogue number 31960) is a rabbit-derived primary antibody validated for Immunohistochemistry, reactive with Human, Mouse, Rat samples. It targets F-box/SPRY domain-containing protein 1 (FBXO45): Component of E3 ubiquitin ligase complex consisting of FBXO45, MYCBP2 and SKP1. Supplied as 100ul at ₪1,301.17; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRabbit
Host / source
Rabbit
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry
UniProt ID
P0C2W1
Gene
FBXO45
Target organism
Homo sapiens
Catalogue number
31960
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: F-box/SPRY domain-containing protein 1 (FBXO45) · Homo sapiens

Component of E3 ubiquitin ligase complex consisting of FBXO45, MYCBP2 and SKP1. Functions in substrate recognition but also plays an important role in assembly of the complex. Required for normal neuromuscular synaptogenesis, axon pathfinding and neuronal migration. Regulates neuron migration during brain development through interaction with N-cadherin/CDH2 after secretion via a non-classical mechanism. Plays a role in the regulation of neurotransmission at mature neurons. May control synaptic activity by controlling UNC13A via ubiquitin dependent pathway.

Subcellular location: Secreted; Postsynaptic cell membrane; Presynaptic cell membrane; Nucleus

Sequence length: 286 aa · 30633 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.