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RNASEL Polyclonal Antibody

31753

RNASEL Polyclonal Antibody

RNASEL Polyclonal Antibody (catalogue number 31753) is a rabbit-derived primary antibody validated for Western blot, reactive with Human, Mouse, Rat samples. It targets 2-5A-dependent ribonuclease (RNASEL): Endoribonuclease that functions in the interferon (IFN) antiviral response. Supplied in 2 pack sizes, from 50ul at ₪1,260.38 to 100ul at ₪1,790.64; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRabbit
Host / source
Rabbit
Reactivity
Human, Mouse, Rat
Applications
Western blot
UniProt ID
Q05823
Gene
RNASEL
Target organism
Homo sapiens
Catalogue number
31753
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: 2-5A-dependent ribonuclease (RNASEL) · Homo sapiens

Endoribonuclease that functions in the interferon (IFN) antiviral response. In INF treated and virus infected cells, RNASEL probably mediates its antiviral effects through a combination of direct cleavage of single-stranded viral RNAs, inhibition of protein synthesis through the degradation of rRNA, induction of apoptosis, and induction of other antiviral genes. RNASEL mediated apoptosis is the result of a JNK-dependent stress-response pathway leading to cytochrome c release from mitochondria and caspase-dependent apoptosis.

Subcellular location: Cytoplasm; Mitochondrion

Tissue specificity: Highly expressed in spleen and thymus followed by prostate, testis, uterus, small intestine, colon and peripheral blood leukocytes

Sequence length: 741 aa · 83533 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.