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SPO11 Polyclonal Antibody

31668

SPO11 Polyclonal Antibody

SPO11 Polyclonal Antibody (catalogue number 31668) is a rabbit-derived primary antibody validated for Western blot, reactive with Rat samples. It targets Meiotic recombination protein SPO11 (SPO11): DNA endonuclease, which specifically mediates DNA cleavage that forms the double-strand breaks (DSB) that initiate meiotic recombination. Supplied in 2 pack sizes, from 50ul at ₪1,260.38 to 100ul at ₪1,790.64; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRabbit
Host / source
Rabbit
Reactivity
Rat
Applications
Western blot
UniProt ID
Q9Y5K1
Gene
SPO11
Target organism
Homo sapiens
Catalogue number
31668
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: Meiotic recombination protein SPO11 (SPO11) · Homo sapiens

DNA endonuclease, which specifically mediates DNA cleavage that forms the double-strand breaks (DSB) that initiate meiotic recombination. SPO11 covalently attaches itself to the 5' DNA strand during DSB formation and each strand is cleaved by a composite active site assembled at the interface of two SPO11 monomers, with the two cleavages staggered to produce a two-nucleotide 5' overhang. SPO11 cleavage site selection is driven by a mild sequence bias and a preference for bendable and underwound DNA.

Subcellular location: Chromosome; Nucleus

Tissue specificity: Highly expressed in testis

Sequence length: 396 aa · 44537 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.