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TGS1 Polyclonal Antibody

31359

TGS1 Polyclonal Antibody

TGS1 Polyclonal Antibody (catalogue number 31359) is a rabbit-derived primary antibody validated for Western blot, reactive with Human, Mouse samples. It targets Trimethylguanosine synthase (TGS1): Catalyzes the 2 serial methylation steps for the conversion of the 7-monomethylguanosine (m(7)G) caps of snRNAs and snoRNAs to a 2,2,7-trimethylguanosine (m(2,2,7)G) cap structure. Supplied in 2 pack sizes, from 50ul at ₪1,260.38 to 100ul at ₪1,790.64; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRabbit
Host / source
Rabbit
Reactivity
Human, Mouse
Applications
Western blot
UniProt ID
Q96RS0
Gene
TGS1
Target organism
Homo sapiens
Catalogue number
31359
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: Trimethylguanosine synthase (TGS1) · Homo sapiens

Catalyzes the 2 serial methylation steps for the conversion of the 7-monomethylguanosine (m(7)G) caps of snRNAs and snoRNAs to a 2,2,7-trimethylguanosine (m(2,2,7)G) cap structure. The enzyme is specific for guanine, and N7 methylation must precede N2 methylation. Hypermethylation of the m7G cap of U snRNAs leads to their concentration in nuclear foci, their colocalization with coilin and the formation of canonical Cajal bodies (CBs). Plays a role in transcriptional regulation

Subcellular location: Cytoplasm; Nucleus, Cajal body; Nucleus, nucleolus

Tissue specificity: Ubiquitously expressed. High expression in heart, skeletal muscle, kidney, liver and placenta

Sequence length: 853 aa · 96620 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.