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MIOS Polyclonal Antibody

30383

MIOS Polyclonal Antibody

MIOS Polyclonal Antibody (catalogue number 30383) is a rabbit-derived primary antibody validated for Western blot, reactive with Human, Mouse, Rat samples. It targets GATOR2 complex protein MIOS (MIOS): As a component of the GATOR2 complex, functions as an activator of the amino acid-sensing branch of the mTORC1 signaling pathway. Supplied in 2 pack sizes, from 50ul at ₪1,260.38 to 100ul at ₪1,790.64; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRabbit
Host / source
Rabbit
Reactivity
Human, Mouse, Rat
Applications
Western blot
UniProt ID
Q9NXC5
Gene
MIOS
Target organism
Homo sapiens
Catalogue number
30383
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: GATOR2 complex protein MIOS (MIOS) · Homo sapiens

As a component of the GATOR2 complex, functions as an activator of the amino acid-sensing branch of the mTORC1 signaling pathway. The GATOR2 complex indirectly activates mTORC1 through the inhibition of the GATOR1 subcomplex. GATOR2 probably acts as an E3 ubiquitin-protein ligase toward GATOR1. In the presence of abundant amino acids, the GATOR2 complex mediates ubiquitination of the NPRL2 core component of the GATOR1 complex, leading to GATOR1 inactivation. In the absence of amino acids, GATOR2 is inhibited, activating the GATOR1 complex.

Subcellular location: Lysosome membrane

Sequence length: 875 aa · 98584 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.