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TNKS Polyclonal Antibody

29962

TNKS Polyclonal Antibody

TNKS Polyclonal Antibody (catalogue number 29962) is a rabbit-derived primary antibody validated for Western blot, reactive with Human samples. It targets Poly [ADP-ribose] polymerase tankyrase-1 (TNKS): Poly-ADP-ribosyltransferase involved in various processes such as Wnt signaling pathway, telomere length and vesicle trafficking. Supplied in 2 pack sizes, from 50ul at ₪1,260.38 to 100ul at ₪1,790.64; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRabbit
Host / source
Rabbit
Reactivity
Human
Applications
Western blot
UniProt ID
O95271
Gene
TNKS
Target organism
Homo sapiens
Catalogue number
29962
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: Poly [ADP-ribose] polymerase tankyrase-1 (TNKS) · Homo sapiens

Poly-ADP-ribosyltransferase involved in various processes such as Wnt signaling pathway, telomere length and vesicle trafficking. Acts as an activator of the Wnt signaling pathway by mediating poly-ADP-ribosylation (PARsylation) of AXIN1 and AXIN2, 2 key components of the beta-catenin destruction complex: poly-ADP-ribosylated target proteins are recognized by RNF146, which mediates their ubiquitination and subsequent degradation. Also mediates PARsylation of BLZF1 and CASC3, followed by recruitment of RNF146 and subsequent ubiquitination.

Subcellular location: Cytoplasm; Golgi apparatus membrane; Cytoplasm, cytoskeleton, microtubule organizing center, centrosome; Nucleus, nuclear pore complex; Chromosome, telomere; Cytoplasm, cytoskeleton, spindle pole

Tissue specificity: Ubiquitous; highest levels in testis

Sequence length: 1327 aa · 142039 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.