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P2RX7 Rabbit Polyclonal Antibody

29572

P2RX7 Rabbit Polyclonal Antibody

P2RX7 Rabbit Polyclonal Antibody (catalogue number 29572) is a rabbit-derived primary antibody validated for Western blot, reactive with Human, Mouse, Rat samples. It targets P2X purinoceptor 7 (P2RX7): ATP-gated nonselective transmembrane cation channel that requires high millimolar concentrations of ATP for activation. Supplied in 2 pack sizes, from 50ul at ₪1,260.38 to 100ul at ₪1,790.64; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRabbit
Host / source
Rabbit
Reactivity
Human, Mouse, Rat
Applications
Western blot
UniProt ID
Q99572
Gene
P2RX7
Target organism
Homo sapiens
Catalogue number
29572
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: P2X purinoceptor 7 (P2RX7) · Homo sapiens

ATP-gated nonselective transmembrane cation channel that requires high millimolar concentrations of ATP for activation. Upon ATP binding, it rapidly opens to allow the influx of small cations Na(+) and Ca(2+), and the K(+) efflux. Also has the ability to form a large pore in the cell membrane, allowing the passage of large cationic molecules. In microglia, may mediate NADPH transport across the plasma membrane. In immune cells, P2RX7 acts as a molecular sensor in pathological inflammatory states by detecting and responding to high local concentrations of extracellar ATP.

Subcellular location: Cell membrane

Tissue specificity: Widely expressed with highest levels in brain and immune tissues

Sequence length: 595 aa · 68585 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.