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DiMethyl-DNMT3A-K44 pAb

29536

DiMethyl-DNMT3A-K44 pAb

DiMethyl-DNMT3A-K44 pAb (catalogue number 29536) is a rabbit-derived primary antibody validated for Immunofluorescence, reactive with Human, Mouse, Rat samples. It targets DNA (cytosine-5)-methyltransferase 3A (Dnmt3a): Required for genome-wide de novo methylation and is essential for the establishment of DNA methylation patterns during development. Supplied in 2 pack sizes, from 50ul at ₪1,260.38 to 100ul at ₪1,790.64; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRabbit
Host / source
Rabbit
Reactivity
Human, Mouse, Rat
Applications
Immunofluorescence
UniProt ID
O88508
Gene
Dnmt3a
Target organism
Mus musculus
Catalogue number
29536
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: DNA (cytosine-5)-methyltransferase 3A (Dnmt3a) · Mus musculus

Required for genome-wide de novo methylation and is essential for the establishment of DNA methylation patterns during development. DNA methylation is coordinated with methylation of histones. It modifies DNA in a non-processive manner and also methylates non-CpG sites. May preferentially methylate DNA linker between 2 nucleosomal cores and is inhibited by histone H1. Plays a role in paternal and maternal imprinting. Required for methylation of most imprinted loci in germ cells. Acts as a transcriptional corepressor for ZBTB18.

Subcellular location: Nucleus; Chromosome; Cytoplasm

Tissue specificity: Isoform 1 is expressed ubiquitously at low levels. Expression of isoform 2 is restricted to tissues containing cells which are undergoing active de novo methylation, including spleen, testis and thymus

Sequence length: 908 aa · 101672 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.