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C9orf72 Polyclonal Antibody

29519

C9orf72 Polyclonal Antibody

C9orf72 Polyclonal Antibody (catalogue number 29519) is a rabbit-derived primary antibody validated for Western blot, Immunohistochemistry, Immunofluorescence, reactive with Human, Mouse, Rat samples. It targets Guanine nucleotide exchange factor C9orf72 (C9orf72): Acts as a guanine-nucleotide releasing factor (GEF) for Rab GTPases by promoting the conversion of inactive RAB-GDP to the active form RAB-GTP. Supplied in 2 pack sizes, from 50ul at ₪1,260.38 to 100ul at ₪1,790.64; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRabbit
Host / source
Rabbit
Reactivity
Human, Mouse, Rat
Applications
Western blot Immunohistochemistry Immunofluorescence
UniProt ID
Q96LT7
Gene
C9orf72
Target organism
Homo sapiens
Catalogue number
29519
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: Guanine nucleotide exchange factor C9orf72 (C9orf72) · Homo sapiens

Acts as a guanine-nucleotide releasing factor (GEF) for Rab GTPases by promoting the conversion of inactive RAB-GDP to the active form RAB-GTP. Acts as a GEF for RAB39A which enables HOPS-mediated autophagosome-lysosome membrane tethering and fusion in mammalian autophagy. Component of the C9orf72-SMCR8 complex where both subunits display GEF activity and that regulates autophagy. As part of the C9orf72-SMCR8-WDR41 (CSW) complex, functions as GEF for RAB8A and RAB39B, thereby promoting autophagosome maturation.

Subcellular location: Cytoplasm; Nucleus; Cytoplasm, P-body; Cytoplasm, Stress granule; Endosome; Lysosome; Cytoplasmic vesicle, autophagosome; Autolysosome; Secreted; Cell projection, axon; Cell projection, growth cone; P

Tissue specificity: Both isoforms are widely expressed, including kidney, lung, liver, heart, testis and several brain regions, such as cerebellum. Also expressed in the frontal cortex and in lymphoblasts (at protein level)

Sequence length: 481 aa · 54328 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.