Loading...
THEM4 Polyclonal Antibody

29505

THEM4 Polyclonal Antibody

THEM4 Polyclonal Antibody (catalogue number 29505) is a rabbit-derived primary antibody validated for Western blot, Immunofluorescence, reactive with Human, Mouse samples. It targets Acyl-coenzyme A thioesterase THEM4 (THEM4): Has acyl-CoA thioesterase activity towards medium and long-chain (C14 to C18) fatty acyl-CoA substrates, and probably plays a role in mitochondrial fatty acid metabolism. Supplied in 2 pack sizes, from 50ul at ₪1,260.38 to 100ul at ₪1,790.64; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRabbit
Host / source
Rabbit
Reactivity
Human, Mouse
Applications
Western blot Immunofluorescence
UniProt ID
Q5T1C6
Gene
THEM4
Target organism
Homo sapiens
Catalogue number
29505
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: Acyl-coenzyme A thioesterase THEM4 (THEM4) · Homo sapiens

Has acyl-CoA thioesterase activity towards medium and long-chain (C14 to C18) fatty acyl-CoA substrates, and probably plays a role in mitochondrial fatty acid metabolism. Plays a role in the apoptotic process, possibly via its regulation of AKT1 activity. According to PubMed:11598301, inhibits AKT1 phosphorylation and activity. According to PubMed:17615157, enhances AKT1 activity by favoring its phosphorylation and translocation to plasma membrane

Subcellular location: Cell membrane; Cell projection, ruffle membrane; Cytoplasm; Mitochondrion; Mitochondrion inner membrane; Mitochondrion intermembrane space

Tissue specificity: Expressed predominantly in skeletal muscle, testis, uterus, brain and kidney. Down-regulated in glioblastoma or glioma compared to non-neoplastic brain due to promoter hypermethylation

Sequence length: 240 aa · 27130 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.