Loading...
TPCN1 Polyclonal Antibody

29451

TPCN1 Polyclonal Antibody

TPCN1 Polyclonal Antibody (catalogue number 29451) is a rabbit-derived primary antibody validated for Western blot, reactive with Mouse, Rat samples. It targets Two pore channel protein 1 (TPCN1): Intracellular channel initially characterized as a non-selective Ca(2+)-permeable channel activated by NAADP (nicotinic acid adenine dinucleotide phosphate), it is also a voltage-gated highly-selective Na(+) channel activated directly by PI(3,5)P2 (phosphatid… Supplied in 2 pack sizes, from 50ul at ₪1,260.38 to 100ul at ₪1,790.64; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRabbit
Host / source
Rabbit
Reactivity
Mouse, Rat
Applications
Western blot
UniProt ID
Q9ULQ1
Gene
TPCN1
Target organism
Homo sapiens
Catalogue number
29451
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: Two pore channel protein 1 (TPCN1) · Homo sapiens

Intracellular channel initially characterized as a non-selective Ca(2+)-permeable channel activated by NAADP (nicotinic acid adenine dinucleotide phosphate), it is also a voltage-gated highly-selective Na(+) channel activated directly by PI(3,5)P2 (phosphatidylinositol 3,5-bisphosphate) that senses pH changes and confers electrical excitability to organelles. Localizes to the early and recycling endosomes membranes where it plays a role in the uptake and processing of proteins and regulates organellar membrane excitability, membrane trafficking and pH homeostasis (Probable).

Subcellular location: Lysosome membrane; Endosome membrane; Early endosome membrane; Recycling endosome membrane

Tissue specificity: Highest expression found in the heart and kidney, and lowest expression found in the spleen

Sequence length: 816 aa · 94147 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.