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MORC3 Polyclonal Antibody

28955

MORC3 Polyclonal Antibody

MORC3 Polyclonal Antibody (catalogue number 28955) is a rabbit-derived primary antibody validated for Western blot, reactive with Human, Mouse samples. It targets MORC family CW-type zinc finger protein 3 (MORC3): Nuclear matrix protein which forms MORC3-NBs (nuclear bodies) via an ATP-dependent mechanism and plays a role in innate immunity by restricting different viruses through modulation of the IFN response. Supplied in 2 pack sizes, from 50ul at ₪1,260.38 to 100ul at ₪1,790.64; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRabbit
Host / source
Rabbit
Reactivity
Human, Mouse
Applications
Western blot
UniProt ID
Q14149
Gene
MORC3
Target organism
Homo sapiens
Catalogue number
28955
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: MORC family CW-type zinc finger protein 3 (MORC3) · Homo sapiens

Nuclear matrix protein which forms MORC3-NBs (nuclear bodies) via an ATP-dependent mechanism and plays a role in innate immunity by restricting different viruses through modulation of the IFN response. Mechanistically, possesses a primary antiviral function through a MORC3-regulated element that activates IFNB1, and this function is guarded by a secondary IFN-repressing function. Sumoylated MORC3-NBs associates with PML-NBs and recruits TP53 and SP100, thus regulating TP53 activity. Binds RNA in vitro.

Subcellular location: Nucleus, nucleoplasm; Nucleus matrix; Nucleus, PML body; Chromosome

Tissue specificity: Expressed in heart, placenta, skeletal muscle, brain, pancreas, lung, liver, but not kidney

Sequence length: 939 aa · 107113 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.