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HERC5 Polyclonal Antibody

28743

HERC5 Polyclonal Antibody

HERC5 Polyclonal Antibody (catalogue number 28743) is a rabbit-derived primary antibody validated for Western blot, reactive with Human, Mouse, Rat samples. It targets E3 ISG15--protein ligase HERC5 (HERC5): Major E3 ligase for ISG15 conjugation. Supplied in 2 pack sizes, from 50ul at ₪1,260.38 to 100ul at ₪1,790.64; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRabbit
Host / source
Rabbit
Reactivity
Human, Mouse, Rat
Applications
Western blot
UniProt ID
Q9UII4
Gene
HERC5
Target organism
Homo sapiens
Catalogue number
28743
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: E3 ISG15--protein ligase HERC5 (HERC5) · Homo sapiens

Major E3 ligase for ISG15 conjugation. Acts as a positive regulator of innate antiviral response in cells induced by interferon. Functions as part of the ISGylation machinery that recognizes target proteins in a broad and relatively non-specific manner. Catalyzes ISGylation of IRF3 which results in sustained activation, it attenuates IRF3-PIN1 interaction, which antagonizes IRF3 ubiquitination and degradation, and boosts the antiviral response.

Subcellular location: Cytoplasm, perinuclear region; Cytoplasm

Tissue specificity: Expressed in testis and to a lesser degree in brain, ovary and placenta. Found in most tissues at low levels

Sequence length: 1024 aa · 116852 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.