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WDR81 Polyclonal Antibody

27781

WDR81 Polyclonal Antibody

WDR81 Polyclonal Antibody (catalogue number 27781) is a rabbit-derived primary antibody validated for Western blot, reactive with Human, Mouse, Rat samples. It targets WD repeat-containing protein 81 (WDR81): Functions as a negative regulator of the PI3 kinase/PI3K activity associated with endosomal membranes via BECN1, a core subunit of the PI3K complex. Supplied in 2 pack sizes, from 50ul at ₪1,260.38 to 100ul at ₪1,790.64; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRabbit
Host / source
Rabbit
Reactivity
Human, Mouse, Rat
Applications
Western blot
UniProt ID
Q562E7
Gene
WDR81
Target organism
Homo sapiens
Catalogue number
27781
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: WD repeat-containing protein 81 (WDR81) · Homo sapiens

Functions as a negative regulator of the PI3 kinase/PI3K activity associated with endosomal membranes via BECN1, a core subunit of the PI3K complex. By modifying the phosphatidylinositol 3-phosphate/PtdInsP3 content of endosomal membranes may regulate endosome fusion, recycling, sorting and early to late endosome transport. It is for instance, required for the delivery of cargos like BST2/tetherin from early to late endosome and thereby participates indirectly to their degradation by the lysosome.

Subcellular location: Early endosome membrane; Late endosome membrane; Lysosome membrane; Cytoplasmic vesicle, autophagosome membrane; Mitochondrion; Cytoplasm, cytosol

Tissue specificity: Widely expressed. In the brain, highest levels in cerebellum and corpus callosum

Sequence length: 1941 aa · 211697 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.