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SBF1 Polyclonal Antibody

27677

SBF1 Polyclonal Antibody

SBF1 Polyclonal Antibody (catalogue number 27677) is a rabbit-derived primary antibody validated for Western blot, reactive with Human, Rat samples. It targets Myotubularin-related protein 5 (SBF1): Acts as an adapter for the phosphatase MTMR2 to regulate MTMR2 catalytic activity and subcellular location. Supplied in 2 pack sizes, from 50ul at ₪1,260.38 to 100ul at ₪1,790.64; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRabbit
Host / source
Rabbit
Reactivity
Human, Rat
Applications
Western blot
UniProt ID
O95248
Gene
SBF1
Target organism
Homo sapiens
Catalogue number
27677
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: Myotubularin-related protein 5 (SBF1) · Homo sapiens

Acts as an adapter for the phosphatase MTMR2 to regulate MTMR2 catalytic activity and subcellular location. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. May function as a guanine nucleotide exchange factor (GEF) activating RAB28. Acts as a suppressor of autophagy in neurons. Together with its binding partner, the phosphatase MTMR2, plays a role in dephosphorylation of phosphoinositides critical for autophagy initiation and autophagosome maturation.

Subcellular location: Cytoplasm; Cytoplasm, perinuclear region; Cell projection, neuron projection

Tissue specificity: Expressed in neurons within the frontal cortex, in neurons of the deep cerebellar nuclei, stellate and basket cells of the molecular layer, and Golgi cells of the granular layer (at protein level)

Sequence length: 1868 aa · 208443 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.