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KREMEN1 Polyclonal Antibody

27463

KREMEN1 Polyclonal Antibody

KREMEN1 Polyclonal Antibody (catalogue number 27463) is a rabbit-derived primary antibody validated for Western blot, reactive with Human, Mouse, Rat samples. It targets Kremen protein 1 (KREMEN1): Receptor for Dickkopf proteins. Supplied in 2 pack sizes, from 50ul at ₪1,260.38 to 100ul at ₪1,790.64; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRabbit
Host / source
Rabbit
Reactivity
Human, Mouse, Rat
Applications
Western blot
UniProt ID
Q96MU8
Gene
KREMEN1
Target organism
Homo sapiens
Catalogue number
27463
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: Kremen protein 1 (KREMEN1) · Homo sapiens

Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6. In the absence of DKK1, potentiates Wnt-beta-catenin signaling by maintaining LRP5 or LRP6 at the cell membrane. Can trigger apoptosis in a Wnt-independent manner and this apoptotic activity is inhibited upon binding of the ligand DKK1. Plays a role in limb development; attenuates Wnt signaling in the developing limb to allow normal limb patterning and can also negatively regulate bone formation.

Subcellular location: Cell membrane

Sequence length: 473 aa · 51744 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.