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DNA-PKcs Mouse mAb

27182

DNA-PKcs Mouse mAb

DNA-PKcs Mouse mAb (catalogue number 27182) is a mouse-derived primary antibody validated for WB IP ICC, reactive with Human samples. It targets DNA-dependent protein kinase catalytic subunit (PRKDC): Serine/threonine-protein kinase that acts as a molecular sensor for DNA damage. Supplied as 100ul at ₪1,301.17; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostMouse
Host / source
Mouse
Reactivity
Human
Applications
WB IP ICC
UniProt ID
P78527
Gene
PRKDC
Target organism
Homo sapiens
Catalogue number
27182
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: DNA-dependent protein kinase catalytic subunit (PRKDC) · Homo sapiens

Serine/threonine-protein kinase that acts as a molecular sensor for DNA damage. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break (DSB) repair and V(D)J recombination. Must be bound to DNA to express its catalytic properties. Promotes processing of hairpin DNA structures in V(D)J recombination by activation of the hairpin endonuclease artemis (DCLRE1C). Recruited by XRCC5 and XRCC6 to DNA ends and is required to (1) protect and align broken ends of DNA, thereby preventing their degradation, (2) and sequester the DSB for repair by NHEJ.

Subcellular location: Nucleus; Nucleus, nucleolus; Cytoplasm, cytosol

Sequence length: 4128 aa · 469089 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.