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TAB1(N-terminus) Mouse mAb

27075

TAB1(N-terminus) Mouse mAb

TAB1(N-terminus) Mouse mAb (catalogue number 27075) is a mouse-derived primary antibody validated for Western blot, reactive with Hu D Ms P Rt samples. It targets TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 (TAB1): Key adapter protein that plays an essential role in JNK and NF-kappa-B activation and proinflammatory cytokines production in response to stimulation with TLRs and cytokines. Supplied as 100ul at ₪1,301.17; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostMouse
Host / source
Mouse
Reactivity
Hu D Ms P Rt
Applications
Western blot
UniProt ID
Q15750
Gene
TAB1
Target organism
Homo sapiens
Catalogue number
27075
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 (TAB1) · Homo sapiens

Key adapter protein that plays an essential role in JNK and NF-kappa-B activation and proinflammatory cytokines production in response to stimulation with TLRs and cytokines. Mechanistically, associates with the catalytic domain of MAP3K7/TAK1 to trigger MAP3K7/TAK1 autophosphorylation leading to its full activation. Similarly, associates with MAPK14 and triggers its autophosphorylation and subsequent activation. In turn, MAPK14 phosphorylates TAB1 and inhibits MAP3K7/TAK1 activation in a feedback control mechanism.

Subcellular location: Cytoplasm, cytosol; Endoplasmic reticulum membrane

Tissue specificity: Ubiquitous

Sequence length: 504 aa · 54644 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.