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SHANK3 Antibody

25486

SHANK3 Antibody

SHANK3 Antibody (catalogue number 25486) is a rabbit-derived primary antibody validated for ELISA WB, reactive with Hu Ms samples. It targets SH3 and multiple ankyrin repeat domains protein 3 (SHANK3): Major scaffold postsynaptic density protein which interacts with multiple proteins and complexes to orchestrate the dendritic spine and synapse formation, maturation and maintenance. Supplied as 100ul at ₪2,157.75; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRabbit
Host / source
Rabbit
Reactivity
Hu Ms
Applications
ELISA WB
UniProt ID
Q9BYB0
Gene
SHANK3
Target organism
Homo sapiens
Catalogue number
25486
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: SH3 and multiple ankyrin repeat domains protein 3 (SHANK3) · Homo sapiens

Major scaffold postsynaptic density protein which interacts with multiple proteins and complexes to orchestrate the dendritic spine and synapse formation, maturation and maintenance. Interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors via complexes with GKAP/PSD-95 and HOMER, respectively, and the actin-based cytoskeleton. Plays a role in the structural and functional organization of the dendritic spine and synaptic junction through the interaction with Arp2/3 and WAVE1 complex as well as the promotion of the F-actin clusters.

Subcellular location: Cytoplasm; Postsynaptic density; Cell projection, dendritic spine

Tissue specificity: Expressed in the cerebral cortex and the cerebellum

Sequence length: 1806 aa · 191338 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.